Detalhe da pesquisa
1.
Tuning of conformational preorganization in model 2',5'- and 3',5'-linked oligonucleotides by 3'- and 2'-O-methoxyethyl modification.
Nucleic Acids Res
; 31(8): 2066-76, 2003 Apr 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-12682357
2.
Probing the influence of stereoelectronic effects on the biophysical properties of oligonucleotides: comprehensive analysis of the RNA affinity, nuclease resistance, and crystal structure of ten 2'-O-ribonucleic acid modifications.
Biochemistry
; 44(25): 9045-57, 2005 Jun 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-15966728
3.
Towards a therapeutic inhibition of dystrophin exon 23 splicing in mdx mouse muscle induced by antisense oligoribonucleotides (splicomers): target sequence optimisation using oligonucleotide arrays.
J Gene Med
; 6(10): 1149-58, 2004 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-15386737
4.
Improving antisense oligonucleotide binding to human serum albumin: dramatic effect of ibuprofen conjugation.
Chembiochem
; 3(12): 1257-60, 2002 Dec 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-12465035