Detalhe da pesquisa
1.
Dynamic reprogramming of the kinome in response to targeted MEK inhibition in triple-negative breast cancer.
Cell
; 149(2): 307-21, 2012 Apr 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-22500798
2.
Small-molecule inhibition of the archetypal UbiB protein COQ8.
Nat Chem Biol
; 19(2): 230-238, 2023 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-36302899
3.
Adaptive chromatin remodeling and transcriptional changes of the functional kinome in tumor cells in response to targeted kinase inhibition.
J Biol Chem
; 298(2): 101525, 2022 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-34958800
4.
New strategies for targeting kinase networks in cancer.
J Biol Chem
; 297(4): 101128, 2021 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-34461089
5.
Kinome profiling of non-Hodgkin lymphoma identifies Tyro3 as a therapeutic target in primary effusion lymphoma.
Proc Natl Acad Sci U S A
; 116(33): 16541-16550, 2019 08 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-31346082
6.
A proteasome-resistant fragment of NIK mediates oncogenic NF-κB signaling in schwannomas.
Hum Mol Genet
; 28(4): 572-583, 2019 02 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-30335132
7.
Epigenetic Mechanisms Regulating Adaptive Responses to Targeted Kinase Inhibitors in Cancer.
Annu Rev Pharmacol Toxicol
; 58: 209-229, 2018 01 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-28934561
8.
PRM-LIVE with Trapped Ion Mobility Spectrometry and Its Application in Selectivity Profiling of Kinase Inhibitors.
Anal Chem
; 93(41): 13791-13799, 2021 10 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-34606255
9.
Far away from the lamppost.
PLoS Biol
; 16(12): e3000067, 2018 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-30532236
10.
Synthesis and Evaluation of Novel 1,2,6-Thiadiazinone Kinase Inhibitors as Potent Inhibitors of Solid Tumors.
Molecules
; 26(19)2021 Sep 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-34641454
11.
Kinome Profiling Identifies Druggable Targets for Novel Human Cytomegalovirus (HCMV) Antivirals.
Mol Cell Proteomics
; 16(4 suppl 1): S263-S276, 2017 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-28237943
12.
Discovery and characterization of an iminocoumarin scaffold as an inhibitor of MEKK2 (MAP3K2).
Biochem Biophys Res Commun
; 496(1): 205-211, 2018 01 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-29309787
13.
Targeting the Breast Cancer Kinome.
J Cell Physiol
; 232(1): 53-60, 2017 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-27186656
14.
Measuring Kinase Activity-A Global Challenge.
J Cell Biochem
; 118(11): 3595-3606, 2017 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-28464261
15.
Weight loss reduces basal-like breast cancer through kinome reprogramming.
Cancer Cell Int
; 16: 26, 2016.
Artigo
em Inglês
| MEDLINE | ID: mdl-27042159
16.
An unbiased proteomic screen reveals caspase cleavage is positively and negatively regulated by substrate phosphorylation.
Mol Cell Proteomics
; 13(5): 1184-97, 2014 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-24556848
17.
Identification of ponatinib and other known kinase inhibitors with potent MEKK2 inhibitory activity.
Biochem Biophys Res Commun
; 463(4): 888-93, 2015 Aug 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-26056008
18.
Coordination of Rho GTPase activities during cell protrusion.
Nature
; 461(7260): 99-103, 2009 Sep 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-19693013
19.
Assessing adaptation of the cancer kinome in response to targeted therapies.
Biochem Soc Trans
; 42(4): 765-9, 2014 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-25109955
20.
The dynamic nature of the kinome.
Biochem J
; 450(1): 1-8, 2013 Feb 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-23343193