Detalhe da pesquisa
1.
Tuning sterol extraction kinetics yields a renal-sparing polyene antifungal.
Nature
; 623(7989): 1079-1085, 2023 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-37938782
2.
In Vitro Activity of APX2041, a New Gwt1 Inhibitor, and In Vivo Efficacy of the Prodrug APX2104 against Aspergillus fumigatus.
Antimicrob Agents Chemother
; 65(10): e0068221, 2021 09 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-34310205
3.
Calcineurin-dependent dephosphorylation of the transcription factor CrzA at specific sites controls conidiation, stress tolerance, and virulence of Aspergillus fumigatus.
Mol Microbiol
; 112(1): 62-80, 2019 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-30927289
4.
Aspergillus fumigatus Cyp51A and Cyp51B Proteins Are Compensatory in Function and Localize Differentially in Response to Antifungals and Cell Wall Inhibitors.
Antimicrob Agents Chemother
; 64(10)2020 09 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-32660997
5.
The tail domain of the Aspergillus fumigatus class V myosin MyoE orchestrates septal localization and hyphal growth.
J Cell Sci
; 131(3)2018 02 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-29222113
6.
The class V myosin interactome of the human pathogen Aspergillus fumigatus reveals novel interactions with COPII vesicle transport proteins.
Biochem Biophys Res Commun
; 527(1): 232-237, 2020 06 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-32446373
7.
FKBP12 dimerization mutations effect FK506 binding and differentially alter calcineurin inhibition in the human pathogen Aspergillus fumigatus.
Biochem Biophys Res Commun
; 526(1): 48-54, 2020 05 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-32192767
8.
Scanning Quadrupole Data-Independent Acquisition, Part A: Qualitative and Quantitative Characterization.
J Proteome Res
; 17(2): 770-779, 2018 02 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-28901143
9.
Scanning Quadrupole Data-Independent Acquisition, Part B: Application to the Analysis of the Calcineurin-Interacting Proteins during Treatment of Aspergillus fumigatus with Azole and Echinocandin Antifungal Drugs.
J Proteome Res
; 17(2): 780-793, 2018 02 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-29251506
10.
Kin1 kinase localizes at the hyphal septum and is dephosphorylated by calcineurin but is dispensable for septation and virulence in the human pathogen Aspergillus fumigatus.
Biochem Biophys Res Commun
; 505(3): 740-746, 2018 11 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-30292408
11.
Caspofungin-Mediated Growth Inhibition and Paradoxical Growth in Aspergillus fumigatus Involve Fungicidal Hyphal Tip Lysis Coupled with Regenerative Intrahyphal Growth and Dynamic Changes in ß-1,3-Glucan Synthase Localization.
Antimicrob Agents Chemother
; 61(10)2017 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-28760907
12.
Caspofungin exposure alters the core septin AspB interactome of Aspergillus fumigatus.
Biochem Biophys Res Commun
; 485(2): 221-226, 2017 04 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-28238781
13.
Distinct Roles of Myosins in Aspergillus fumigatus Hyphal Growth and Pathogenesis.
Infect Immun
; 84(5): 1556-64, 2016 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-26953327
14.
Forging the ring: from fungal septins' divergent roles in morphology, septation and virulence to factors contributing to their assembly into higher order structures.
Microbiology (Reading)
; 162(9): 1527-1534, 2016 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-27559018
15.
Heat shock protein 90 (Hsp90): A novel antifungal target against Aspergillus fumigatus.
Crit Rev Microbiol
; 42(2): 310-21, 2016.
Artigo
em Inglês
| MEDLINE | ID: mdl-25243616
16.
Potential Microbiological Effects of Higher Dosing of Echinocandins.
Clin Infect Dis
; 61 Suppl 6: S669-77, 2015 Dec 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-26567286
17.
Hsp70 and the Cochaperone StiA (Hop) Orchestrate Hsp90-Mediated Caspofungin Tolerance in Aspergillus fumigatus.
Antimicrob Agents Chemother
; 59(8): 4727-33, 2015 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-26014950
18.
Calcium-Mediated Induction of Paradoxical Growth following Caspofungin Treatment Is Associated with Calcineurin Activation and Phosphorylation in Aspergillus fumigatus.
Antimicrob Agents Chemother
; 59(8): 4946-55, 2015 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-26055379
19.
The Aspergillus fumigatus septins play pleiotropic roles in septation, conidiation, and cell wall stress, but are dispensable for virulence.
Fungal Genet Biol
; 81: 41-51, 2015 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-26051489
20.
Antifungal activity of compounds targeting the Hsp90-calcineurin pathway against various mould species.
J Antimicrob Chemother
; 70(5): 1408-11, 2015 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-25558076