Detalhe da pesquisa
1.
Effects of serotonin in the hippocampus: how SSRIs and multimodal antidepressants might regulate pyramidal cell function.
CNS Spectr
; 21(2): 143-61, 2016 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-26346726
2.
Sodium channel cleavage is associated with aberrant neuronal activity and cognitive deficits in a mouse model of Alzheimer's disease.
J Neurosci
; 33(16): 7020-6, 2013 Apr 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-23595759
3.
Inhibition of MEK-ERK signaling reduces seizures in two mouse models of tuberous sclerosis complex.
Epilepsy Res
; 181: 106890, 2022 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-35219048
4.
Responses of trigeminal ganglion neurons during natural whisking behaviors in the awake rat.
Neuron
; 53(1): 117-33, 2007 Jan 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-17196535
5.
Impact of overactive bladder on the brain: central sequelae of a visceral pathology.
Proc Natl Acad Sci U S A
; 105(30): 10589-94, 2008 Jul 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-18645186
6.
Antisense oligonucleotides increase Scn1a expression and reduce seizures and SUDEP incidence in a mouse model of Dravet syndrome.
Sci Transl Med
; 12(558)2020 08 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-32848094
7.
Aß-accelerated neurodegeneration caused by Alzheimer's-associated ACE variant R1279Q is rescued by angiotensin system inhibition in mice.
Sci Transl Med
; 12(563)2020 09 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-32998969
8.
Novel brain permeant mTORC1/2 inhibitors are as efficacious as rapamycin or everolimus in mouse models of acquired partial epilepsy and tuberous sclerosis complex.
Neuropharmacology
; 180: 108297, 2020 12 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-32890589
9.
The 5-HT6 receptor antagonist idalopirdine potentiates the effects of donepezil on gamma oscillations in the frontal cortex of anesthetized and awake rats without affecting sleep-wake architecture.
Neuropharmacology
; 113(Pt A): 45-59, 2017 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-27647493
10.
Acute dosing of vortioxetine strengthens event-related brain activity associated with engagement of attention and cognitive functioning in rats.
Brain Res
; 1664: 37-47, 2017 06 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-28366617
11.
Differentiated effects of the multimodal antidepressant vortioxetine on sleep architecture: Part 2, pharmacological interactions in rodents suggest a role of serotonin-3 receptor antagonism.
J Psychopharmacol
; 29(10): 1092-105, 2015 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-26174134
12.
Serotonergic Regulation of Prefrontal Cortical Circuitries Involved in Cognitive Processing: A Review of Individual 5-HT Receptor Mechanisms and Concerted Effects of 5-HT Receptors Exemplified by the Multimodal Antidepressant Vortioxetine.
ACS Chem Neurosci
; 6(7): 970-86, 2015 Jul 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-25746856
13.
Treatment of cognitive dysfunction in major depressive disorder--a review of the preclinical evidence for efficacy of selective serotonin reuptake inhibitors, serotonin-norepinephrine reuptake inhibitors and the multimodal-acting antidepressant vortioxetine.
Eur J Pharmacol
; 753: 19-31, 2015 Apr 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-25107284
14.
Can pharmaco-electroencephalography help improve survival of central nervous system drugs in early clinical development?
Drug Discov Today
; 19(3): 282-8, 2014 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-23954252
15.
Vortioxetine disinhibits pyramidal cell function and enhances synaptic plasticity in the rat hippocampus.
J Psychopharmacol
; 28(10): 891-902, 2014 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-25122043
16.
Predator stress engages corticotropin-releasing factor and opioid systems to alter the operating mode of locus coeruleus norepinephrine neurons.
Neuropharmacology
; 62(4): 1737-45, 2012 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-22210331
17.
Nicotine receptor subtype-specific effects on auditory evoked oscillations and potentials.
PLoS One
; 7(7): e39775, 2012.
Artigo
em Inglês
| MEDLINE | ID: mdl-22911690
18.
Aligning strategies for using EEG as a surrogate biomarker: a review of preclinical and clinical research.
Biochem Pharmacol
; 81(12): 1408-21, 2011 Jun 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-20937262
19.
Altered intrinsic neuronal excitability and reduced Na+ currents in a mouse model of Alzheimer's disease.
Neurobiol Aging
; 32(11): 2109.e1-14, 2011 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-21794952
20.
A cog in cognition: how the alpha 7 nicotinic acetylcholine receptor is geared towards improving cognitive deficits.
Pharmacol Ther
; 122(3): 302-11, 2009 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-19351547