Detalhe da pesquisa
1.
Factors affecting product association as a mechanism of host-cell protein persistence in bioprocessing.
Biotechnol Bioeng
; 121(4): 1284-1297, 2024 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-38240126
2.
Identification and characterization of CHO host-cell proteins in monoclonal antibody bioprocessing.
Biotechnol Bioeng
; 121(1): 291-305, 2024 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-37877536
3.
Characterization and implications of host-cell protein aggregates in biopharmaceutical processing.
Biotechnol Bioeng
; 120(4): 1068-1080, 2023 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-36585356
4.
Comprehensive assessment of host cell protein expression after extended culture and bioreactor production of CHO cell lines.
Biotechnol Bioeng
; 119(8): 2221-2238, 2022 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-35508759
5.
GDC-0084 inhibits cutaneous squamous cell carcinoma cell growth.
Biochem Biophys Res Commun
; 503(3): 1941-1948, 2018 09 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-30072096
6.
Knockout of a difficult-to-remove CHO host cell protein, lipoprotein lipase, for improved polysorbate stability in monoclonal antibody formulations.
Biotechnol Bioeng
; 114(5): 1006-1015, 2017 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-27943242
7.
Minimum Transendothelial Electrical Resistance Thresholds for the Study of Small and Large Molecule Drug Transport in a Human in Vitro Blood-Brain Barrier Model.
Mol Pharm
; 13(12): 4191-4198, 2016 12 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-27934481
8.
Improved protease digestion conditions for membrane protein detection.
Electrophoresis
; 36(15): 1690-8, 2015 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-25884272
9.
PUMA binding induces partial unfolding within BCL-xL to disrupt p53 binding and promote apoptosis.
Nat Chem Biol
; 9(3): 163-8, 2013 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-23340338
10.
Behavior of host-cell-protein-rich aggregates in antibody capture and polishing chromatography.
J Chromatogr A
; 1702: 464081, 2023 Aug 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-37244165
11.
Analytical characterization of host-cell-protein-rich aggregates in monoclonal antibody solutions.
Biotechnol Prog
; 39(4): e3343, 2023.
Artigo
em Inglês
| MEDLINE | ID: mdl-37020359
12.
Disrupting the intermolecular self-association of Itk enhances T cell signaling.
J Immunol
; 184(8): 4228-35, 2010 Apr 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-20237289
13.
Itk tyrosine kinase substrate docking is mediated by a nonclassical SH2 domain surface of PLCgamma1.
Proc Natl Acad Sci U S A
; 106(50): 21143-8, 2009 Dec 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-19955438
14.
Emerging Role of IL-10 in Hypertrophic Scars.
Front Med (Lausanne)
; 7: 438, 2020.
Artigo
em Inglês
| MEDLINE | ID: mdl-32974363
15.
Monitoring Ligand-Induced Protein Ordering in Drug Discovery.
J Mol Biol
; 428(6): 1290-1303, 2016 Mar 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-26812210
16.
A case study of proline isomerization in cell signaling.
Front Biosci
; 10: 385-97, 2005 Jan 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-15574377
17.
Scaffold Protein SLP-76 Primes PLCγ1 for Activation by ITK-Mediated Phosphorylation.
J Mol Biol
; 427(17): 2734-47, 2015 Aug 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-25916191
18.
Complex and extensive post-transcriptional regulation revealed by integrative proteomic and transcriptomic analysis of metabolite stress response in Clostridium acetobutylicum.
Biotechnol Biofuels
; 8: 81, 2015.
Artigo
em Inglês
| MEDLINE | ID: mdl-26269711
19.
In Vivo Consequences of Disrupting SH3-Mediated Interactions of the Inducible T-Cell Kinase.
J Signal Transduct
; 2012: 694386, 2012.
Artigo
em Inglês
| MEDLINE | ID: mdl-22649724
20.
SH2-dependent autophosphorylation within the Tec family kinase Itk.
J Mol Biol
; 391(1): 164-77, 2009 Aug 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-19523959