Detalhe da pesquisa
1.
Cyclic-disulfide-based prodrugs for cytosol-specific drug delivery.
Angew Chem Int Ed Engl
; 53(51): 14046-50, 2014 Dec 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-25346363
2.
Application of a Rat Liver Drug Bioactivation Transcriptional Response Assay Early in Drug Development That Informs Chemically Reactive Metabolite Formation and Potential for Drug-induced Liver Injury.
Toxicol Sci
; 177(1): 281-299, 2020 09 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-32559301
3.
The carboxy-terminal Neh3 domain of Nrf2 is required for transcriptional activation.
Mol Cell Biol
; 25(24): 10895-906, 2005 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-16314513
4.
The pathways and molecular mechanisms regulating Nrf2 activation in response to chemical stress.
Free Radic Biol Med
; 37(4): 433-41, 2004 Aug 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-15256215
5.
Prevalence and counts of Salmonella and enterohemorrhagic Escherichia coli in raw, shelled runner peanuts.
J Food Prot
; 76(10): 1668-75, 2013 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-24112565
6.
Role of protein phosphorylation in the regulation of NF-E2-related factor 2 activity.
Methods Enzymol
; 378: 286-301, 2004.
Artigo
em Inglês
| MEDLINE | ID: mdl-15038976
7.
The Nrf2-antioxidant response element signaling pathway and its activation by oxidative stress.
J Biol Chem
; 284(20): 13291-5, 2009 May 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-19182219
8.
A mutation of Keap1 found in breast cancer impairs its ability to repress Nrf2 activity.
Biochem Biophys Res Commun
; 362(4): 816-21, 2007 Nov 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-17822677
9.
Nrf2 controls constitutive and inducible expression of ARE-driven genes through a dynamic pathway involving nucleocytoplasmic shuttling by Keap1.
J Biol Chem
; 280(37): 32485-92, 2005 Sep 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-16000310
10.
Regulatory mechanisms controlling gene expression mediated by the antioxidant response element.
Annu Rev Pharmacol Toxicol
; 43: 233-60, 2003.
Artigo
em Inglês
| MEDLINE | ID: mdl-12359864
11.
CYP1A1 induction by pyridine and its metabolites in HepG2 cells.
Arch Biochem Biophys
; 404(2): 326-34, 2002 Aug 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-12147272
12.
Phosphorylation of Nrf2 at Ser-40 by protein kinase C regulates antioxidant response element-mediated transcription.
J Biol Chem
; 277(45): 42769-74, 2002 Nov 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-12198130
13.
Increased protein stability as a mechanism that enhances Nrf2-mediated transcriptional activation of the antioxidant response element. Degradation of Nrf2 by the 26 S proteasome.
J Biol Chem
; 278(7): 4536-41, 2003 Feb 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-12446695