Detalhe da pesquisa
1.
The Plant Derived 3-3'-Diindolylmethane (DIM) Behaves as CB2 Receptor Agonist in Prostate Cancer Cellular Models.
Int J Mol Sci
; 24(4)2023 Feb 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-36835033
2.
M3 Receptor Pathway Stimulates Rapid Transcription of the CB1 Receptor Activation through Calcium Signalling and the CNR1 Gene Promoter.
Int J Mol Sci
; 24(2)2023 Jan 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-36674826
3.
Synthesis and In Vitro Characterization of Selective Cannabinoid CB2 Receptor Agonists: Biological Evaluation against Neuroblastoma Cancer Cells.
Molecules
; 27(9)2022 May 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-35566369
4.
Design, synthesis, and pharmacological profiling of cannabinoid 1 receptor allosteric modulators: Preclinical efficacy of C2-group GAT211 congeners for reducing intraocular pressure.
Bioorg Med Chem
; 50: 116421, 2021 11 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-34634617
5.
Disease-associated polymorphisms within the conserved ECR1 enhancer differentially regulate the tissue-specific activity of the cannabinoid-1 receptor gene promoter; implications for cannabinoid pharmacogenetics.
Hum Mutat
; 41(1): 291-298, 2020 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31608546
6.
Synthetic bioactive olivetol-related amides: The influence of the phenolic group in cannabinoid receptor activity.
Bioorg Med Chem
; 28(11): 115513, 2020 06 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-32340793
7.
CB2 cannabinoid receptor agonist enantiomers HU-433 and HU-308: An inverse relationship between binding affinity and biological potency.
Proc Natl Acad Sci U S A
; 112(28): 8774-9, 2015 Jul 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-26124120
8.
Synthesis, radio-synthesis and in vitro evaluation of terminally fluorinated derivatives of HU-210 and HU-211 as novel candidate PET tracers.
Org Biomol Chem
; 15(9): 2086-2096, 2017 Mar 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-28210722
9.
Modulation of food consumption and sleep-wake cycle in mice by the neutral CB1 antagonist ABD459.
Behav Pharmacol
; 26(3): 289-303, 2015 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-25356730
10.
Endocannabinoids and Their Pharmacological Actions.
Handb Exp Pharmacol
; 231: 1-37, 2015.
Artigo
em Inglês
| MEDLINE | ID: mdl-26408156
11.
The 90th Birthday of Professor Raphael Mechoulam, a Top Cannabinoid Scientist and Pioneer.
Int J Mol Sci
; 21(20)2020 10 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-33081122
12.
In-vivo pharmacological evaluation of the CB1-receptor allosteric modulator Org-27569.
Behav Pharmacol
; 25(2): 182-5, 2014 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-24603340
13.
Structure-affinity relationships and pharmacological characterization of new alkyl-resorcinol cannabinoid receptor ligands: Identification of a dual cannabinoid receptor/TRPA1 channel agonist.
Bioorg Med Chem
; 22(17): 4770-83, 2014 Sep 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-25065940
14.
Direct suppression of CNS autoimmune inflammation via the cannabinoid receptor CB1 on neurons and CB2 on autoreactive T cells.
Nat Med
; 13(4): 492-7, 2007 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-17401376
15.
CB(1) receptor allosteric modulators display both agonist and signaling pathway specificity.
Mol Pharmacol
; 83(2): 322-38, 2013 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-23160940
16.
Modulation of L-α-lysophosphatidylinositol/GPR55 mitogen-activated protein kinase (MAPK) signaling by cannabinoids.
J Biol Chem
; 287(1): 91-104, 2012 Jan 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-22027819
17.
Displacement Binding Assay Using Human Cannabinoid CB2 Receptor-Transfected Cells.
Methods Mol Biol
; 2576: 111-118, 2023.
Artigo
em Inglês
| MEDLINE | ID: mdl-36152180
18.
Cyclic AMP Assay Using Human Cannabinoid CB2 Receptor-Transfected Cells.
Methods Mol Biol
; 2576: 171-179, 2023.
Artigo
em Inglês
| MEDLINE | ID: mdl-36152185
19.
Motor-like Tics are Mediated by CB2 Cannabinoid Receptor-dependent and Independent Mechanisms Associated with Age and Sex.
Mol Neurobiol
; 59(8): 5070-5083, 2022 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-35666403
20.
CB1 receptor binding sites for NAM and PAM: A first approach for studying, new nbutyldiphenylcarboxamides as allosteric modulators.
Eur J Pharm Sci
; 169: 106088, 2022 Feb 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-34863873