Detalhe da pesquisa
1.
The small molecule inhibitor NAV-2729 has a complex target profile including multiple ADP-ribosylation factor regulatory proteins.
J Biol Chem
; 299(3): 102992, 2023 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-36758799
2.
A lysine-rich cluster in the N-BAR domain of ARF GTPase-activating protein ASAP1 is necessary for binding and bundling actin filaments.
J Biol Chem
; 298(3): 101700, 2022 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-35143843
3.
In vitro reconstitution reveals cooperative mechanisms of adapter protein-mediated activation of phospholipase C-γ1 in T cells.
J Biol Chem
; 298(3): 101680, 2022 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-35124007
4.
Small GTPase ARF6 Is a Coincidence-Detection Code for RPH3A Polarization in Neutrophil Polarization.
J Immunol
; 204(4): 1012-1021, 2020 02 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-31924649
5.
Interaction of the N terminus of ADP-ribosylation factor with the PH domain of the GTPase-activating protein ASAP1 requires phosphatidylinositol 4,5-bisphosphate.
J Biol Chem
; 294(46): 17354-17370, 2019 11 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-31591270
6.
Functional Expression and Characterization of Human Myristoylated-Arf1 in Nanodisc Membrane Mimetics.
Biochemistry
; 58(10): 1423-1431, 2019 03 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-30735034
7.
The tuberous sclerosis complex subunit TBC1D7 is stabilized by Akt phosphorylation-mediated 14-3-3 binding.
J Biol Chem
; 293(42): 16142-16159, 2018 10 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-30143532
8.
ARAP2 inhibits Akt independently of its effects on focal adhesions.
Biol Cell
; 110(12): 257-270, 2018 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-30144359
9.
Direct Functional Interaction of the Kinesin-13 Family Member Kinesin-like Protein 2A (Kif2A) and Arf GAP with GTP-binding Protein-like, Ankyrin Repeats and PH Domains1 (AGAP1).
J Biol Chem
; 291(41): 21350-21362, 2016 10 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-27531749
10.
The Arf GTPase-activating Protein, ASAP1, Binds Nonmuscle Myosin 2A to Control Remodeling of the Actomyosin Network.
J Biol Chem
; 291(14): 7517-26, 2016 Apr 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-26893376
11.
Inhibition of Cytohesins Protects against Genetic Models of Motor Neuron Disease.
J Neurosci
; 35(24): 9088-105, 2015 Jun 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-26085633
12.
Insights into Ubiquitination from the Unique Clamp-like Binding of the RING E3 AO7 to the E2 UbcH5B.
J Biol Chem
; 290(51): 30225-39, 2015 Dec 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-26475854
13.
The Arf6 GTPase-activating proteins ARAP2 and ACAP1 define distinct endosomal compartments that regulate integrin α5ß1 traffic.
J Biol Chem
; 289(44): 30237-30248, 2014 Oct 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-25225293
14.
ARAP2 signals through Arf6 and Rac1 to control focal adhesion morphology.
J Biol Chem
; 288(8): 5849-60, 2013 Feb 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-23295182
15.
The N termini of a-subunit isoforms are involved in signaling between vacuolar H+-ATPase (V-ATPase) and cytohesin-2.
J Biol Chem
; 288(8): 5896-913, 2013 Feb 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-23288846
16.
Point mutations in Arf1 reveal cooperative effects of the N-terminal extension and myristate for GTPase-activating protein catalytic activity.
PLoS One
; 19(4): e0295103, 2024.
Artigo
em Inglês
| MEDLINE | ID: mdl-38574162
17.
The pleckstrin homology (PH) domain of the Arf exchange factor Brag2 is an allosteric binding site.
J Biol Chem
; 287(29): 24273-83, 2012 Jul 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-22613714
18.
GTP-binding protein-like domain of AGAP1 is protein binding site that allosterically regulates ArfGAP protein catalytic activity.
J Biol Chem
; 287(21): 17176-17185, 2012 May 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-22453919
19.
Ciliary targeting motif VxPx directs assembly of a trafficking module through Arf4.
EMBO J
; 28(3): 183-92, 2009 Feb 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-19153612
20.
Fusion-negative rhabdomyosarcoma orthotopic tongue xenografts for study of invasion, intravasation and metastasis in live animals.
bioRxiv
; 2023 Nov 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-38076999