Detalhe da pesquisa
1.
Steroid-Induced Ocular Hypertension in Mice Is Differentially Reduced by Selective EP2, EP3, EP4, and IP Prostanoid Receptor Agonists.
Int J Mol Sci
; 25(6)2024 Mar 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-38542305
2.
Identifying new drugs and targets to treat rapidly elevated intraocular pressure for angle closure and secondary glaucomas to curb visual impairment and prevent blindness.
Exp Eye Res
; 232: 109444, 2023 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-36958427
3.
FP and EP2 prostanoid receptor agonist drugs and aqueous humor outflow devices for treating ocular hypertension and glaucoma.
Exp Eye Res
; 229: 109415, 2023 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-36803996
4.
The Role of Autophagy in Chemical Proteasome Inhibition Model of Retinal Degeneration.
Int J Mol Sci
; 22(14)2021 Jul 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-34298888
5.
Preclinical pharmacology, ocular tolerability and ocular hypotensive efficacy of a novel non-peptide bradykinin mimetic small molecule.
Exp Eye Res
; 128: 170-80, 2014 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-25307520
6.
FR-190997, a nonpeptide bradykinin B2-receptor partial agonist, is a potent and efficacious intraocular pressure lowering agent in ocular hypertensive cynomolgus monkeys.
Drug Dev Res
; 75(4): 211-23, 2014 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-24796320
7.
Human experience and efficacy of omidenepag isopropyl (Eybelis®; Omlonti®): Discovery to approval of the novel non-prostaglandin EP2-receptor-selective agonist ocular hypotensive drug.
Curr Opin Pharmacol
; 74: 102426, 2024 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-38168596
8.
Protein expression, biochemical pharmacology of signal transduction, and relation to intraocular pressure modulation by bradykinin B2 receptors in ciliary muscle.
Mol Vis
; 19: 1356-70, 2013.
Artigo
em Inglês
| MEDLINE | ID: mdl-23805043
9.
Neuroaxonal and cellular damage/protection by prostanoid receptor ligands, fatty acid derivatives and associated enzyme inhibitors.
Neural Regen Res
; 18(1): 5-17, 2023 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-35799502
10.
Electrical, Electromagnetic, Ultrasound Wave Therapies, and Electronic Implants for Neuronal Rejuvenation, Neuroprotection, Axonal Regeneration, and IOP Reduction.
J Ocul Pharmacol Ther
; 39(8): 477-498, 2023 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-36126293
11.
Recently Approved Drugs for Lowering and Controlling Intraocular Pressure to Reduce Vision Loss in Ocular Hypertensive and Glaucoma Patients.
Pharmaceuticals (Basel)
; 16(6)2023 May 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-37375739
12.
Elevated Intraocular Pressure and Glaucomatous Optic Neuropathy: Genes to Disease Mechanisms, Therapeutic Drugs, and Gene Therapies.
Pharmaceuticals (Basel)
; 16(6)2023 Jun 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-37375817
13.
Gene therapies and gene product-based drug candidates for normalizing and preserving tissue functions in animal models of ocular hypertension and glaucoma.
Mol Aspects Med
; 94: 101218, 2023 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-37976898
14.
Ocular Treatments Targeting Separate Prostaglandin Receptors in Mice Exhibit Alterations in Intraocular Pressure and Optic Nerve Lipidome.
J Ocul Pharmacol Ther
; 39(8): 541-550, 2023 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-37267222
15.
MicroRNA profile of extracellular vesicles released by Müller glial cells.
Front Cell Neurosci
; 17: 1325114, 2023.
Artigo
em Inglês
| MEDLINE | ID: mdl-38303973
16.
PAF-induced inflammatory and immuno-allergic ophthalmic diseases and their mitigation with PAF receptor antagonists: Cell and nuclear effects.
Biofactors
; 48(6): 1226-1249, 2022 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-35594054
17.
Degeneration of retina-brain components and connections in glaucoma: Disease causation and treatment options for eyesight preservation.
Curr Res Neurobiol
; 3: 100037, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-36685768
18.
Neuroprotection in neurodegenerations of the brain and eye: Lessons from the past and directions for the future.
Front Neurol
; 13: 964197, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-36034312
19.
Therapeutic Drugs and Devices for Tackling Ocular Hypertension and Glaucoma, and Need for Neuroprotection and Cytoprotective Therapies.
Front Pharmacol
; 12: 729249, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-34603044
20.
NPR-B natriuretic peptide receptors in human corneal epithelium: mRNA, immunohistochemistochemical, protein, and biochemical pharmacology studies.
Mol Vis
; 16: 1241-52, 2010 Jul 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-20664698