Detalhe da pesquisa
1.
ANG2 Blockade Diminishes Proangiogenic Cerebrovascular Defects Associated With Models of Hereditary Hemorrhagic Telangiectasia.
Arterioscler Thromb Vasc Biol
; 43(8): 1384-1403, 2023 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-37288572
2.
Platform Reagents Enable Synthesis of Ligand-Directed Covalent Probes: Study of Cannabinoid Receptor 2 in Live Cells.
J Am Chem Soc
; 145(28): 15094-15108, 2023 07 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-37401816
3.
Investigations into mRNA Lipid Nanoparticles Shelf-Life Stability under Nonfrozen Conditions.
Mol Pharm
; 20(12): 6492-6503, 2023 Dec 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-37975733
4.
NF-κB activation in astrocytes drives a stage-specific beneficial neuroimmunological response in ALS.
EMBO J
; 37(16)2018 08 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-29875132
5.
Lysophosphatidic Acid Is a Proinflammatory Stimulus of Renal Tubular Epithelial Cells.
Int J Mol Sci
; 23(13)2022 Jul 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-35806457
6.
New Technologies in Clinical Trials in Corneal Diseases and Limbal Stem Cell Deficiency: Review from the European Vision Institute Special Interest Focus Group Meeting.
Ophthalmic Res
; 64(2): 145-167, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-32634808
7.
TGR5-dependent hepatoprotection through the regulation of biliary epithelium barrier function.
Gut
; 69(1): 146-157, 2020 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30723104
8.
Angiopoietin-2 Inhibition Rescues Arteriovenous Malformation in a Smad4 Hereditary Hemorrhagic Telangiectasia Mouse Model.
Circulation
; 139(17): 2049-2063, 2019 04 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-30744395
9.
Pharmacological activation of TGR5 promotes intestinal growth via a GLP-2-dependent pathway in mice.
Am J Physiol Gastrointest Liver Physiol
; 318(5): G980-G987, 2020 05 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-32308039
10.
Highly Selective, Amine-Derived Cannabinoid Receptor 2 Probes.
Chemistry
; 26(6): 1380-1387, 2020 Jan 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-31961047
11.
Selective Cannabinoid 2 Receptor Agonists as Potential Therapeutic Drugs for the Treatment of Endotoxin-Induced Uveitis.
Molecules
; 24(18)2019 Sep 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-31540271
12.
Pharmacologic targeting of the ATX/LPA axis attenuates bleomycin-induced pulmonary fibrosis.
Pulm Pharmacol Ther
; 52: 32-40, 2018 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-30201409
13.
A Novel Selective Inverse Agonist of the CB2 Receptor as a Radiolabeled Tool Compound for Kinetic Binding Studies.
Mol Pharmacol
; 92(4): 389-400, 2017 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-28747489
14.
From Structure-Activity Relationships on Thiazole Derivatives to the In Vivo Evaluation of a New Radiotracer for Cannabinoid Subtype 2 PET Imaging.
Mol Pharm
; 14(11): 4064-4078, 2017 11 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-28968497
15.
TGR5 is essential for bile acid-dependent cholangiocyte proliferation in vivo and in vitro.
Gut
; 65(3): 487-501, 2016 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-26420419
16.
LYSOPHOSPHATIDIC ACIDS AND AUTOTAXIN IN RETINAL VEIN OCCLUSION.
Retina
; 36(12): 2311-2318, 2016 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-27648638
17.
Highly potent and selective cannabinoid receptor 2 agonists: initial hit optimization of an adamantyl hit series identified from high-through-put screening.
Bioorg Med Chem Lett
; 23(5): 1177-81, 2013 Mar 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-23380378
18.
Discovery and optimisation of 1-hydroxyimino-3,3-diphenylpropanes, a new class of orally active GPBAR1 (TGR5) agonists.
Bioorg Med Chem Lett
; 23(16): 4627-32, 2013 Aug 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-23831134
19.
Real-time measurements of vascular permeability in the mouse eye using vitreous fluorophotometry.
Sci Rep
; 13(1): 9226, 2023 06 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-37286795
20.
Effects of Cathepsin S Inhibition in the Age-Related Dry Eye Phenotype.
Invest Ophthalmol Vis Sci
; 64(11): 7, 2023 08 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-37540176