Detalhe da pesquisa
1.
Racial and ethnic differences in plasma biomarker eligibility for a preclinical Alzheimer's disease trial.
Alzheimers Dement
; 2024 Apr 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-38629508
2.
Clinical validation of the PrecivityAD2 blood test: A mass spectrometry-based test with algorithm combining %p-tau217 and Aß42/40 ratio to identify presence of brain amyloid.
Alzheimers Dement
; 20(5): 3179-3192, 2024 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-38491912
3.
Novel allele-dependent role for APOE in controlling the rate of synapse pruning by astrocytes.
Proc Natl Acad Sci U S A
; 113(36): 10186-91, 2016 09 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-27559087
4.
The effect of angiotensin receptor neprilysin inhibitor, sacubitril/valsartan, on central nervous system amyloid-ß concentrations and clearance in the cynomolgus monkey.
Toxicol Appl Pharmacol
; 323: 53-65, 2017 05 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-28315356
5.
microRNA-33 Regulates ApoE Lipidation and Amyloid-ß Metabolism in the Brain.
J Neurosci
; 35(44): 14717-26, 2015 Nov 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-26538644
6.
ApoE influences amyloid-ß (Aß) clearance despite minimal apoE/Aß association in physiological conditions.
Proc Natl Acad Sci U S A
; 110(19): E1807-16, 2013 May 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-23620513
7.
Low-density lipoprotein receptor overexpression enhances the rate of brain-to-blood Aß clearance in a mouse model of ß-amyloidosis.
Proc Natl Acad Sci U S A
; 109(38): 15502-7, 2012 Sep 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-22927427
8.
The binding of apolipoprotein E to oligomers and fibrils of amyloid-ß alters the kinetics of amyloid aggregation.
Biochemistry
; 53(40): 6323-31, 2014 Oct 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-25207746
9.
Nicotinamide mononucleotide adenylyl transferase 1 protects against acute neurodegeneration in developing CNS by inhibiting excitotoxic-necrotic cell death.
Proc Natl Acad Sci U S A
; 108(47): 19054-9, 2011 Nov 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-22058226
10.
Associations of sleep duration and daytime sleepiness with plasma amyloid beta and cognitive performance in cognitively unimpaired, middle-aged and older African Americans.
Sleep
; 47(1)2024 01 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-38011629
11.
Low-density lipoprotein receptor represents an apolipoprotein E-independent pathway of Aß uptake and degradation by astrocytes.
J Biol Chem
; 287(17): 13959-71, 2012 Apr 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-22383525
12.
Independent study demonstrates amyloid probability score accurately indicates amyloid pathology.
Ann Clin Transl Neurol
; 10(5): 765-778, 2023 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-36975407
13.
Critical role of astroglial apolipoprotein E and liver X receptor-α expression for microglial Aß phagocytosis.
J Neurosci
; 31(19): 7049-59, 2011 May 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-21562267
14.
Assessment of a Plasma Amyloid Probability Score to Estimate Amyloid Positron Emission Tomography Findings Among Adults With Cognitive Impairment.
JAMA Netw Open
; 5(4): e228392, 2022 04 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-35446396
15.
The ß-subunit of ATP synthase is involved in cellular uptake and resecretion of apoA-I but does not control apoA-I-induced lipid efflux in adipocytes.
Mol Cell Biochem
; 348(1-2): 155-64, 2011 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-21069432
16.
A blood-based diagnostic test incorporating plasma Aß42/40 ratio, ApoE proteotype, and age accurately identifies brain amyloid status: findings from a multi cohort validity analysis.
Mol Neurodegener
; 16(1): 30, 2021 05 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-33933117
17.
The PrecivityAD™ test: Accurate and reliable LC-MS/MS assays for quantifying plasma amyloid beta 40 and 42 and apolipoprotein E proteotype for the assessment of brain amyloidosis.
Clin Chim Acta
; 519: 267-275, 2021 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-34015303
18.
Characterization of apoA-I-dependent lipid efflux from adipocytes and role of ABCA1.
Mol Cell Biochem
; 343(1-2): 115-24, 2010 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-20535530
19.
Apolipoprotein E associated with reconstituted high-density lipoprotein-like particles is protected from aggregation.
FEBS Lett
; 593(11): 1144-1153, 2019 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-31058310
20.
Correction: Blood-brain barrier-associated pericytes internalize and clear aggregated amyloid-ß42 by LRP1-dependent apolipoprotein E isoform-specific mechanism.
Mol Neurodegener
; 19(1): 27, 2024 Mar 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-38519970