Detalhe da pesquisa
1.
Negligible impact of rare autoimmune-locus coding-region variants on missing heritability.
Nature
; 498(7453): 232-5, 2013 Jun 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-23698362
2.
Mosaic PPM1D mutations are associated with predisposition to breast and ovarian cancer.
Nature
; 493(7432): 406-10, 2013 Jan 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-23242139
3.
The chromosome 6q22.33 region is associated with age at diagnosis of type 1 diabetes and disease risk in those diagnosed under 5 years of age.
Diabetologia
; 61(1): 147-157, 2018 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-28983737
4.
Dissection of a Complex Disease Susceptibility Region Using a Bayesian Stochastic Search Approach to Fine Mapping.
PLoS Genet
; 11(6): e1005272, 2015 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-26106896
5.
Detection and correction of artefacts in estimation of rare copy number variants and analysis of rare deletions in type 1 diabetes.
Hum Mol Genet
; 24(6): 1774-90, 2015 Mar 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-25424174
6.
Regulatory T Cell Responses in Participants with Type 1 Diabetes after a Single Dose of Interleukin-2: A Non-Randomised, Open Label, Adaptive Dose-Finding Trial.
PLoS Med
; 13(10): e1002139, 2016 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-27727279
7.
Large-scale genetic fine mapping and genotype-phenotype associations implicate polymorphism in the IL2RA region in type 1 diabetes.
Nat Genet
; 39(9): 1074-82, 2007 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-17676041
8.
Robust associations of four new chromosome regions from genome-wide analyses of type 1 diabetes.
Nat Genet
; 39(7): 857-64, 2007 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-17554260
9.
IL-21 production by CD4+ effector T cells and frequency of circulating follicular helper T cells are increased in type 1 diabetes patients.
Diabetologia
; 58(4): 781-90, 2015 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-25652388
10.
A method for gene-based pathway analysis using genomewide association study summary statistics reveals nine new type 1 diabetes associations.
Genet Epidemiol
; 38(8): 661-70, 2014 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-25371288
11.
Postthymic expansion in human CD4 naive T cells defined by expression of functional high-affinity IL-2 receptors.
J Immunol
; 190(6): 2554-66, 2013 Mar 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-23418630
12.
A genome-wide association study of nonsynonymous SNPs identifies a type 1 diabetes locus in the interferon-induced helicase (IFIH1) region.
Nat Genet
; 38(6): 617-9, 2006 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-16699517
13.
Plasma concentrations of soluble IL-2 receptor α (CD25) are increased in type 1 diabetes and associated with reduced C-peptide levels in young patients.
Diabetologia
; 57(2): 366-72, 2014 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-24264051
14.
A hybrid qPCR/SNP array approach allows cost efficient assessment of KIR gene copy numbers in large samples.
BMC Genomics
; 15: 274, 2014 Apr 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-24720548
15.
Seven newly identified loci for autoimmune thyroid disease.
Hum Mol Genet
; 21(23): 5202-8, 2012 Dec 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-22922229
16.
Long-range DNA looping and gene expression analyses identify DEXI as an autoimmune disease candidate gene.
Hum Mol Genet
; 21(2): 322-33, 2012 Jan 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-21989056
17.
Returning findings within longitudinal cohort studies: the 1958 birth cohort as an exemplar.
Emerg Themes Epidemiol
; 11: 10, 2014.
Artigo
em Inglês
| MEDLINE | ID: mdl-25126104
18.
Population structure, differential bias and genomic control in a large-scale, case-control association study.
Nat Genet
; 37(11): 1243-6, 2005 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-16228001
19.
Localization of type 1 diabetes susceptibility to the MHC class I genes HLA-B and HLA-A.
Nature
; 450(7171): 887-92, 2007 Dec 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-18004301
20.
Shared and distinct genetic variants in type 1 diabetes and celiac disease.
N Engl J Med
; 359(26): 2767-77, 2008 Dec 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-19073967