Detalhe da pesquisa
1.
Chemotherapy re-use versus anti-angiogenic monotherapy as the third-line treatment of patients with metastatic colorectal cancer: a real-world cohort study.
BMC Cancer
; 24(1): 302, 2024 Mar 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-38443891
2.
Sintilimab Plus Apatinib and Chemotherapy as Second/Third-Line treatment for Advanced Gastric or Gastroesophageal Junction Adenocarcinoma: a prospective, Single-Arm, phase II trial.
BMC Cancer
; 23(1): 211, 2023 Mar 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-36872337
3.
Synthesis of biotinylated-LPG as a chemical biology tool enabling discovery of ALCAT1 modulators.
Bioorg Med Chem Lett
; 72: 128861, 2022 09 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-35718103
4.
Discovery of an Allosteric, Inactive Conformation-Selective Inhibitor of Full-Length HPK1 Utilizing a Kinase Cascade Assay.
Biochemistry
; 60(41): 3114-3124, 2021 10 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-34608799
5.
A carboxylic acid isostere screen of the DHODH inhibitor Brequinar.
Bioorg Med Chem Lett
; 30(22): 127589, 2020 11 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-33007394
6.
Hit-to-lead optimization and discovery of a potent, and orally bioavailable G protein coupled receptor kinase 2 (GRK2) inhibitor.
Bioorg Med Chem Lett
; 30(23): 127602, 2020 12 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-33038544
7.
FGF23 regulates atrial fibrosis in atrial fibrillation by mediating the STAT3 and SMAD3 pathways.
J Cell Physiol
; 234(11): 19502-19510, 2019 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-30953354
8.
Pd Nanoparticles Confined in the Porous Graphene-like Carbon Nanosheets for Olefin Hydrogenation.
Langmuir
; 34(43): 12809-12814, 2018 10 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-30269506
9.
Discovery of Inactive Conformation-Selective Kinase Inhibitors by Utilizing Cascade Assays.
Biochemistry
; 56(34): 4449-4456, 2017 08 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-28574701
10.
Spectroscopic and Computational Investigations of Ligand Binding to IspH: Discovery of Non-diphosphate Inhibitors.
Chembiochem
; 18(10): 914-920, 2017 05 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-28253432
11.
The Streptococcus suis transcriptional landscape reveals adaptation mechanisms in pig blood and cerebrospinal fluid.
RNA
; 20(6): 882-98, 2014 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-24759092
12.
Coupling Oxygen Consumption with Hydrocarbon Oxidation in Bacterial Multicomponent Monooxygenases.
Acc Chem Res
; 48(9): 2632-9, 2015 Sep 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-26293615
13.
Impact of incomplete revascularization of coronary artery disease on long-term cardiac outcomes. Retrospective comparison of angiographic and myocardial perfusion imaging criteria for completeness.
J Nucl Cardiol
; 23(3): 546-55, 2016 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-26037599
14.
Mechanistic Studies of the Anticancer Activity of An Octahedral Hexanuclear Pt(II) Cage.
Inorganica Chim Acta
; 452: 125-129, 2016 Oct 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-27818526
15.
Structure, function and inhibition of the two- and three-domain 4Fe-4S IspG proteins.
Proc Natl Acad Sci U S A
; 109(22): 8558-63, 2012 May 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-22586085
16.
Diiron oxidation state control of substrate access to the active site of soluble methane monooxygenase mediated by the regulatory component.
J Am Chem Soc
; 136(6): 2244-7, 2014 Feb 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-24476336
17.
Electron transfer control in soluble methane monooxygenase.
J Am Chem Soc
; 136(27): 9754-62, 2014 Jul 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-24937475
18.
Bioorganometallic chemistry with IspG and IspH: structure, function, and inhibition of the [Fe(4)S(4)] proteins involved in isoprenoid biosynthesis.
Angew Chem Int Ed Engl
; 53(17): 4294-310, 2014 Apr 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-24481599
19.
Gastric cancer secreted miR-214-3p inhibits the anti-angiogenesis effect of apatinib by suppressing ferroptosis in vascular endothelial cells.
Oncol Res
; 32(3): 489-502, 2024.
Artigo
em Inglês
| MEDLINE | ID: mdl-38370339
20.
Discovery of Alternative Binding Poses through Fragment-Based Identification of DHODH Inhibitors.
ACS Med Chem Lett
; 15(3): 381-387, 2024 Mar 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-38505861