Mycobacterium tuberculosis spoligotypes and drug-resistant characterization from Beira compared to genotypes circulating in Mozambique
Anselmo, Lívia Maria Pala; Conceição, Emilyn Costa; Namburete, Evangelina; Feliciano, Cinara; Spindola, Silvana; Sola, Christophe; Bollela, Valdes Roberto.
Rev. Soc. Bras. Med. Trop
; 52: e20190257, 2019. tab, graf
Artículo
en Inglés
| LILACS | ID: biblio-1057252
Abstract INTRODUCTION Mozambique is one of three countries with high prevalence of tuberculosis (TB), TB/human immunodeficiency virus coinfection, and multidrug-resistant TB. We aimed to describe Mycobacterium tuberculosis spoligotypes circulating among drug resistant (DR) strains from Beira, Mozambique comparing them with genotypes in the country.
METHODS:
We performed spoligotyping of 79 M. tuberculosis suspected of DR-TB compared all spoligotype patterns published on the international database and PubMed.RESULTS:
Both in Beira and Mozambique (n=578), the main clades were Latin-American-Mediterranean, East-African-Indian, Beijing and T, with no extensively DR TB cases.CONCLUSIONS:
Beira and Mozambique share the same population genetic structure of M. tuberculosis.
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BR1.1
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