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Synthesis, crystal structure, and anti-breast cancer activity of a novel metal-porphyrinic complex [YK(TCPP)(OH)2·(solvents)x]
Liu, J-C; Gu, J-J; Zhang, Y-S.
Afiliación
  • Liu, J-C; Huaihe Hospital of Henan University. Department of Radiotherapy. Kaifeng. CN
  • Gu, J-J; Huaihe Hospital of Henan University. Department of Radiotherapy. Kaifeng. CN
  • Zhang, Y-S; Huaihe Hospital of Henan University. Department of Radiotherapy. Kaifeng. CN
Rev. bras. pesqui. méd. biol ; Braz. j. med. biol. res;51(1): e6858, 2018. tab, graf
Article en En | LILACS | ID: biblio-889001
Biblioteca responsable: BR1.1
ABSTRACT
A novel heterometallic metal-porphyrinic framework (MPFs) built from Y and K ions as nods and meso-tetra(4-carboxyphenyl)porphyrin as linkers has been successfully synthesized and characterized. The single crystal X-ray diffraction indicated that this complex 1 exhibited a bilayered architecture of the porphyrins, which is seldom seen in MPFs. In addition, in vitro anticancer activity of complex 1 on three human breast cancer cells (BT474, SKBr-3 and ZR-75-30) was further determined.
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Texto completo: 1 Banco de datos: LILACS Asunto principal: Porfirinas / Neoplasias de la Mama / Estructuras Metalorgánicas / Antineoplásicos Tipo de estudio: Evaluation_studies Límite: Humans Idioma: En Revista: Braz. j. med. biol. res / Rev. bras. pesqui. méd. biol Asunto de la revista: BIOLOGIA / MEDICINA Año: 2018 Tipo del documento: Article País de afiliación: China
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Texto completo: 1 Banco de datos: LILACS Asunto principal: Porfirinas / Neoplasias de la Mama / Estructuras Metalorgánicas / Antineoplásicos Tipo de estudio: Evaluation_studies Límite: Humans Idioma: En Revista: Braz. j. med. biol. res / Rev. bras. pesqui. méd. biol Asunto de la revista: BIOLOGIA / MEDICINA Año: 2018 Tipo del documento: Article País de afiliación: China