The paper presents the results of a research project focused on the development of a monitoring and evaluation system for programs of control and prevention of cancer in Venezuela. Policy models were designed and empirically validated for the following types of canceruterine cervix, the breast, lung, the stomach and prostate. Analysis of correlation indicated that stomach cancer was positively correlated to variations in illiteracy and GNP per capita. In the case of cancer of prostate the correlation was negative. Analysis of time series using standardized mortality rates indicate that mortality rates for lung cancer, the breast cancer and prostate cancer increased historically. In the case of stomach cancer the mortality rate decreased historically. In the case of the uterine cervixcancer there was no significant relation. The experience acquired in these analyses would be useful to refine policy models using complementary data and including states as units of analysis.