Cell surface distribution of lectin receptors determined by resonance energy transfer.
Nature
; 264(5585): 411-5, 1976 Dec 02.
Article
en En
| MEDLINE
| ID: mdl-1004566
ABSTRACT
The surface topography of concanavalin A (con A) bound to normal and transformed murine fibroblasts has been studied by a new technique involving fluorescence resonance energy transfer (RET), RET can provide a high resolution "map" of the distances separating con A-receptor complexes in single living cells. The distribution of con A is non-random in both normal and transformed cells, but sites are more closely approximated in the transformed. Approximation is induced by the con A but occurs at extremely slow rates indicating that the topography is not primarily determined by simple diffusion of complexes.
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Banco de datos:
MEDLINE
Asunto principal:
Receptores de Droga
/
Receptores de Concanavalina A
/
Membrana Celular
/
Transformación Celular Neoplásica
Idioma:
En
Revista:
Nature
Año:
1976
Tipo del documento:
Article