Glutathione S-transferase alpha levels in epileptic and healthy women preconceptionally and throughout pregnancy.
Gynecol Obstet Invest
; 48(2): 89-92, 1999.
Article
en En
| MEDLINE
| ID: mdl-10460997
ABSTRACT
We studied plasma GSTA1-1 concentrations in preconceptionally recruited epileptic women who received antiepileptic drugs (n = 99) and a control group of healthy women (n = 106). Mean plasma GSTA1-1 concentrations in the control group did not show significant changes preconceptionally and throughout pregnancy. Six weeks postpartum, however, a significant increase in the mean plasma GSTA1-1 concentration (p < 0.001) was found as compared to preconceptional levels and levels during pregnancy. The mean plasma GSTA1-1 concentration in epileptic women was significantly higher in the 4th gestational week compared to those determined in healthy pregnant women (1.68 versus 1.08 microg/l, p < 0.001). Values between the groups in the second and third trimester and postpartum period showed no significant differences.
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Banco de datos:
MEDLINE
Asunto principal:
Complicaciones del Embarazo
/
Epilepsia
/
Glutatión Transferasa
Tipo de estudio:
Clinical_trials
Límite:
Female
/
Humans
/
Pregnancy
Idioma:
En
Revista:
Gynecol Obstet Invest
Año:
1999
Tipo del documento:
Article
País de afiliación:
Países Bajos