Atropisomerism of the C-1-C'-1 axis of 2,2',8,8'-unsubstituted 1,1'-binaphthyl derivatives.
J Org Chem
; 66(15): 5042-7, 2001 Jul 27.
Article
en En
| MEDLINE
| ID: mdl-11463254
ABSTRACT
The Suzuki coupling of optically active (S)-binaphthyl bromide 10 with (S)-binaphthyl boronic acid 11 produced a diastereomeric mixture of tetrahydroxyquaternaphthyls 4. The coupling products 4as well as their derivatives 5-7 can be considered as members of the family of 1,1'-binaphthyl-3,3'-diols. The C-1-C'-1 axis of all these compounds was found to have an unusually high rotational barrier. Generally, the barrier is higher for derivatives having more bulky substituents at the 3 and 3' positions.
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Banco de datos:
MEDLINE
Idioma:
En
Revista:
J Org Chem
Año:
2001
Tipo del documento:
Article
País de afiliación:
China