A prospective natural history study of inclusion body myositis: implications for clinical trials.
Neurology
; 57(3): 548-50, 2001 Aug 14.
Article
en En
| MEDLINE
| ID: mdl-11502935
ABSTRACT
Eleven patients with untreated inclusion body myositis (IBM) were prospectively studied during a 6-month period that included muscle strength, lean body mass, and muscle mass measurements. There was an overall quantifiable mean decline in percent of predicted normal muscle strength of 4% from baseline in a 6-month period, but one third of patients showed no change or slight improvements in strength. Short-term treatment trials in IBM will require large numbers of patients to detect slowing, arrest, or even slight improvement in muscle strength.
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Banco de datos:
MEDLINE
Asunto principal:
Ensayos Clínicos como Asunto
/
Miositis por Cuerpos de Inclusión
Tipo de estudio:
Prognostic_studies
/
Risk_factors_studies
Límite:
Aged
/
Female
/
Humans
/
Male
/
Middle aged
Idioma:
En
Revista:
Neurology
Año:
2001
Tipo del documento:
Article
País de afiliación:
Reino Unido