[Quantification of metallothionein induced with selenium by using competitive ELISA].
Sheng Wu Hua Xue Yu Sheng Wu Wu Li Xue Bao (Shanghai)
; 34(2): 245-7, 2002 Mar.
Article
en Zh
| MEDLINE
| ID: mdl-12007005
ABSTRACT
Metallothionein induced by selenium was assayed with competitive ELISA. It was found that in control mice, the liver contained (2.47+/-0.90) microgram MT/g wet weight tissue, while the mice administered with ZnSO(4) contained (8.15+/-2.20) microgram MT/g wet weight liver tissue and the mice given with selenium malt contained (12.80+/-1.44) microgram MT/g wet weight liver. A significant difference was found between the control and the latter two groups (P<0.05, P<0.05). The MT content of selenium group was significantly higher than the zinc group. It is suggested that the selenium was more potent in induction of MT and was a stronger inducer than ZnSO(4) in its effective dose range, therefore selenium may be developed into a novel and safe MT inducer.
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Banco de datos:
MEDLINE
Asunto principal:
Selenio
/
Ensayo de Inmunoadsorción Enzimática
/
Metalotioneína
Límite:
Animals
Idioma:
Zh
Revista:
Sheng Wu Hua Xue Yu Sheng Wu Wu Li Xue Bao (Shanghai)
Año:
2002
Tipo del documento:
Article
País de afiliación:
China