Somatostatin in the management of gastrointestinal fistulas. A multicenter trial.
Arch Surg
; 127(1): 97-9; discussion 100, 1992 Jan.
Article
en En
| MEDLINE
| ID: mdl-1346491
ABSTRACT
To evaluate the effectiveness of treatment with total parenteral nutrition (TPN) alone (group A) or combined with continuous intravenous infusion of somatostatin (group B) in postoperative gastrointestinal fistulas, a multicenter, controlled and prospective randomized trial was designed. We present the results obtained after the evaluation of 40 cases (group A, n = 20; group B, n = 20). No significant differences among these treatment schedules were observed in the percentage of closure of fistulas (group A, 81.25%; group B, 85%), but patients treated with total parenteral nutrition plus somatostatin had the fistulas close within a significantly shorter period of time. Moreover, this treatment was associated with a significantly lower morbidity. These preliminary results indicate that somatostatin is a useful therapeutic complement in the conservative treatment of patients with gastrointestinal fistulas.
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Banco de datos:
MEDLINE
Asunto principal:
Somatostatina
/
Fístula Intestinal
/
Fístula Pancreática
Tipo de estudio:
Clinical_trials
/
Etiology_studies
/
Observational_studies
/
Risk_factors_studies
Límite:
Adult
/
Aged
/
Female
/
Humans
/
Male
/
Middle aged
Idioma:
En
Revista:
Arch Surg
Año:
1992
Tipo del documento:
Article
País de afiliación:
España