Prevalence of asthma with aspirin hypersensitivity in the adult population of Poland.
Allergy
; 58(10): 1064-6, 2003 Oct.
Article
en En
| MEDLINE
| ID: mdl-14510727
ABSTRACT
BACKGROUND:
Acetylsalicylic acid (ASA) and other nonsteroid anti-inflammatory drugs (NSAIDs) are reported to account for 21-25% of all adverse drug reactions. Some asthmatics may react to ASA and other NSAIDs with acute bronchoconstriction, profuse rhinorrhea and skin flushing. This is a distinct clinical syndrome called aspirin-induced asthma (AIA). The prevalence of AIA among asthmatic patients in Poland has not been previously assessed.METHODS:
A questionnaire survey of 12,970 adults of both sexes, randomly selected from the population of Poland.RESULTS:
The prevalence of AIA in the general population of Poland was estimated as 0.6%. Thirty patients (4.3%; 95% CI 2.8-5.8) of 703 asthmatics (5.4% of general population) reported symptoms attesting to hypersensitivity to aspirin. In 27% of them the reactions were precipitated by aspirin, whereas in the remaining subjects by other NSAIDs.CONCLUSIONS:
The prevalence of AIA in Poland is 4.3%, being somewhat lower than in Finland and Australia, where it was recently reported to account for 8.8 and 10.9% of the adult asthmatics, respectively. These figures indicate that aspirin hypersensitivity might be a significant community problem.
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Banco de datos:
MEDLINE
Asunto principal:
Asma
/
Antiinflamatorios no Esteroideos
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Aspirina
/
Hipersensibilidad a las Drogas
Tipo de estudio:
Clinical_trials
/
Prevalence_studies
/
Risk_factors_studies
Límite:
Adolescent
/
Adult
/
Aged
/
Child
/
Child, preschool
/
Female
/
Humans
/
Infant
/
Male
/
Middle aged
País/Región como asunto:
Europa
Idioma:
En
Revista:
Allergy
Año:
2003
Tipo del documento:
Article
País de afiliación:
Polonia