Mutation analysis of three genes encoding novel LKB1-interacting proteins, BRG1, STRADalpha, and MO25alpha, in Peutz-Jeghers syndrome.
Br J Cancer
; 92(6): 1126-9, 2005 Mar 28.
Article
en En
| MEDLINE
| ID: mdl-15756273
ABSTRACT
Mutations in LKB1 lead to Peutz-Jeghers syndrome (PJS). However, only a subset of PJS patients harbours LKB1 mutations. We performed a mutation analysis of three genes encoding novel LKB1-interacting proteins, BRG1, STRADalpha, and MO25alpha, in 28 LKB1-negative PJS patients. No disease-causing mutations were detected in the studied genes in PJS patients from different European populations.
Texto completo:
1
Banco de datos:
MEDLINE
Asunto principal:
Factores de Transcripción
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Síndrome de Peutz-Jeghers
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Proteínas Nucleares
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Proteínas Adaptadoras del Transporte Vesicular
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Proteínas Adaptadoras Transductoras de Señales
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Mutación
Límite:
Humans
Idioma:
En
Revista:
Br J Cancer
Año:
2005
Tipo del documento:
Article
País de afiliación:
Finlandia