Antimicrobial prophylaxis for major head and neck cancer surgery with piperacillin and ornidazole.
J Laryngol Otol
; 106(5): 409-11, 1992 May.
Article
en En
| MEDLINE
| ID: mdl-1613366
ABSTRACT
A prospective study in 53 eligible patients, undergoing major head and neck cancer surgery was carried out to assess the combination of an ureido penicillin, piperacillin with a nitro imidazole agent, ornidazole, in order to prevent post-operative general and wound infections. Both antibiotics were administered for five days. Each patient had piperacillin 4 gm every eight hours and ornidazole 1 gm every 24 hours. The overall rate of infections was 13.2 per cent (n = 7), with 3.8 per cent (n = 2) wound infections and 11.3 per cent (n = 6) general infections (one patient presented both complications). There was no wound infection in the total surgery group (n = 12). General infections who only consisted of pneumonias were respectively 12.2 per cent (n = 5) in the group with partial procedures (n = 41) and 8.3 per cent (n = 1) in the total surgery group. This antibioprophylaxis can be recommended in major oncological neck surgery, specially in the case of partial procedures.
Buscar en Google
Banco de datos:
MEDLINE
Asunto principal:
Ornidazol
/
Piperacilina
/
Complicaciones Posoperatorias
/
Premedicación
/
Infección de Heridas
/
Neoplasias de Cabeza y Cuello
Tipo de estudio:
Observational_studies
/
Risk_factors_studies
Límite:
Adult
/
Aged
/
Female
/
Humans
/
Male
/
Middle aged
Idioma:
En
Revista:
J Laryngol Otol
Asunto de la revista:
OTORRINOLARINGOLOGIA
Año:
1992
Tipo del documento:
Article
País de afiliación:
Francia