Synthesis of 3-amino-1,2,4-benzothiadi- azine 1,1-dioxides via a tandem aza-Wittig/heterocumulene annulation.
J Org Chem
; 70(24): 10206-9, 2005 Nov 25.
Article
en En
| MEDLINE
| ID: mdl-16292875
ABSTRACT
[reaction see text] Reaction of o-azidobenzenesulfonamides with polymer-supported triphenylphosphine affords the corresponding iminophosphoranes. Subsequent reaction with isocyanates gives 3-amino-1,2,4-benzothiadiazine 1,1-dioxides in high yields and purities. The reaction has been successfully applied to the synthesis of derivatives with various substituents at the 2- and 3-positions and in the benzenoid ring.
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Banco de datos:
MEDLINE
Asunto principal:
Compuestos Organofosforados
/
Sulfonamidas
/
Azidas
/
Triazinas
/
Isocianatos
Idioma:
En
Revista:
J Org Chem
Año:
2005
Tipo del documento:
Article
País de afiliación:
Estados Unidos