Adenosine 3',5'-monophosphate analogs promote a circular morphology of cultured Schwannoma cells.
Science
; 187(4172): 179-81, 1975 Jan 17.
Article
en En
| MEDLINE
| ID: mdl-163036
ABSTRACT
Dibutyryl adenosine 3',5'-monophosphate (dibutyrl cycle AMP) and 8-bromo cyclic AMP stimulated cells cultured from a rat Schwannoma to change their morphology from irregularly shaped to flattened circular and hollow circular forms within 30 minutes. The change in shape was specifically effected by analogs of cyclic AMP and cyclic AMP elevating agents, was reversible after removal of these additives, and was prevented by vinblastine and cytochalasin b, but was not affected by actinomycin D or cycloheximide.
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Banco de datos:
MEDLINE
Asunto principal:
Células Cultivadas
/
AMP Cíclico
/
Neurilemoma
Idioma:
En
Revista:
Science
Año:
1975
Tipo del documento:
Article