CEACAM1: contact-dependent control of immunity.
Nat Rev Immunol
; 6(6): 433-46, 2006 Jun.
Article
en En
| MEDLINE
| ID: mdl-16724098
ABSTRACT
The carcinoembryonic-antigen-related cell-adhesion molecule (CEACAM) family of proteins has been implicated in various intercellular-adhesion and intracellular-signalling-mediated effects that govern the growth and differentiation of normal and cancerous cells. Recent studies show that there is an important role for members of the CEACAM family in modulating the immune responses associated with infection, inflammation and cancer. In this Review, we consider the evidence for CEACAM involvement in immunity, with a particular emphasis on CEACAM1, which functions as a regulatory co-receptor for both lymphoid and myeloid cell types.
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Banco de datos:
MEDLINE
Asunto principal:
Antígenos CD
/
Moléculas de Adhesión Celular
/
Comunicación Celular
/
Células Mieloides
/
Inmunidad Celular
/
Tejido Linfoide
Límite:
Animals
/
Humans
Idioma:
En
Revista:
Nat Rev Immunol
Asunto de la revista:
ALERGIA E IMUNOLOGIA
Año:
2006
Tipo del documento:
Article
País de afiliación:
Canadá