Is depth of anesthesia, as assessed by the Bispectral Index, related to postoperative cognitive dysfunction and recovery?
Anesth Analg
; 103(3): 633-40, 2006 Sep.
Article
en En
| MEDLINE
| ID: mdl-16931673
ABSTRACT
We randomized 74 patients to either a lower Bispectral Index (BIS) regimen (median BIS, 38.9) or a higher BIS regimen (mean BIS, 50.7) during the surgical procedure. Preoperatively and 4-6 wk after surgery, the patients' cognitive status was assessed with a cognitive test battery consisting of processing speed index, working memory index, and verbal memory index. Processing speed index was 113.7 +/- 1.5 (mean +/- se) in the lower BIS group versus 107.9 +/- 1.4 in the higher BIS group (P = 0.006). No difference was observed in the other two test battery components. Somewhat deeper levels of anesthesia were therefore associated with better cognitive function 4-6 wk postoperatively, particularly with respect to the ability to process information.
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Banco de datos:
MEDLINE
Asunto principal:
Cognición
/
Anestésicos Intravenosos
/
Adyuvantes Anestésicos
/
Memoria
Tipo de estudio:
Clinical_trials
Límite:
Aged
/
Female
/
Humans
/
Male
/
Middle aged
Idioma:
En
Revista:
Anesth Analg
Año:
2006
Tipo del documento:
Article
País de afiliación:
Estados Unidos