Adjuvant chemotherapy in esophageal cancer.
Rays
; 31(1): 31-5, 2006.
Article
en En
| MEDLINE
| ID: mdl-16999373
ABSTRACT
Esophageal cancer with high incidence and mortality rates plays a major clinical and social role. Adjuvant radiotherapy, chemotherapy and combined chemoradiation are used for esophageal cancer patients after esophagectomy. Outcomes of these approaches are analyzed in the literature. Three randomized clinical trials and three retrospective series were reviewed; they provided a representative pattern of available data. From their analysis some critical aspects emerged in relation to the statistical design of the few, now available randomized clinical trials. The number of patients enrolled is too low to verify minimal improvements in outcomes. Therefore, to-date there is not definite evidence in the literature supporting the role of adjuvant chemotherapy in patients undergoing surgery for esophageal cancer.
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Banco de datos:
MEDLINE
Asunto principal:
Neoplasias Esofágicas
/
Esofagectomía
/
Quimioterapia Adyuvante
/
Antineoplásicos
Tipo de estudio:
Clinical_trials
Límite:
Humans
Idioma:
En
Revista:
Rays
Año:
2006
Tipo del documento:
Article
País de afiliación:
Italia