Topographic indications of emerging keratoconus in teenage New Zealanders.
Cornea
; 26(3): 312-8, 2007 Apr.
Article
en En
| MEDLINE
| ID: mdl-17413959
ABSTRACT
PURPOSE:
To screen a population of teenagers for emerging topographic signs of keratoconus (KC), with particular reference to ethnicity.METHODS:
Corneal topography, visual acuity, and an environmental risk factor analysis were included in a screening program designed to identify early indications of potential KC in teenagers. Two schools from central North Island, New Zealand, were invited to participate one with predominantly Maori/Polynesian students and the other with students of mainly European descent.RESULTS:
A total of 198 Maori/Polynesian, 16.8 +/- 1.05 years of age, and 243 European students, 16.2 +/- 1.3 years of age, participated in the study. Corneal topography suggestive strongly of KC was evident in 3 Maori/Polynesian [1.2%; 95% confidence interval (CI) 0.3-4.3] and no European students (0%; 95% CI, 0%-1.5%). Anomalous corneal topography reminiscent of emerging KC in at least 1 eye were found in 19% (95% CI, 15.6%-22.9%). A significant difference (P = 0.0014) in the percentage of suspected KC was found between European students (12.9%; 95% CI, 9.2%-17.9%) and Maori/Polynesian students (26.9%; 95% CI, 21.0%-33.7%). In multivariate analyses, the significant independent predictors of probable or suspected KC included being Maori/Polynesian [odds ratio (OR) = 2.1; 95% CI, 1.25-3.54; P = 0.0052], increasing age (OR = 1.4; 95% CI, 1.10-1.80; P = 0.0067), and a history of hayfever (OR = 2.0; 95% CI, 1.16-3.59; P = 0.013). Topographical indicators that were associated significantly with suspected KC included central keratometry (P < 0.0001), astigmatism (P = 0.014), and inferior-superior asymmetry (P < 0.0001).CONCLUSIONS:
Although only a longitudinal study will determine the proportion of true KC candidates, these data provide evidence of ethnicity-related differences in corneal topography in teenage New Zealanders.
Buscar en Google
Banco de datos:
MEDLINE
Asunto principal:
Córnea
/
Topografía de la Córnea
/
Queratocono
Tipo de estudio:
Clinical_trials
/
Etiology_studies
/
Observational_studies
/
Prognostic_studies
/
Risk_factors_studies
Límite:
Adolescent
/
Child
/
Female
/
Humans
/
Male
País/Región como asunto:
Oceania
Idioma:
En
Revista:
Cornea
Año:
2007
Tipo del documento:
Article
País de afiliación:
Nueva Zelanda