Skeletal diversity through radical cyclization of tetrahydropyridine scaffolds.

Dandapani, Sivaraman; Duduta, Mihai; Panek, James S; Porco, John A

Dandapani, Sivaraman; Duduta, Mihai; Panek, James S; Porco, John A.

Afiliación

Dandapani S; Department of Chemistry and Center for Chemical Methodology and Library Development, Boston University, 590 Commonwealth Avenue, Boston, Massachusetts 02215, USA.

Org Lett ; 9(19): 3849-52, 2007 Sep 13.

Article en En | MEDLINE | ID: mdl-17713919

ABSTRACT

ABSTRACT

Suitably functionalized tetrahydropyridines (methyl pipecolates) have been used as conformationally biased templates for radical cyclizations to access benzoisoquinuclidines and linearly fused indenopiperidines. Variation of skeletal types is determined by location of a radical-initiating element.

Asunto(s)

Hidrógeno/química; Piridinas/síntesis química; Alquilación; Carbono/química; Ciclización; Radicales Libres/química; Hidantoínas/química; Modelos Moleculares; Estructura Molecular; Piridinas/química

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Banco de datos: MEDLINE Asunto principal: Piridinas / Hidrógeno Idioma: En Revista: Org Lett Asunto de la revista: BIOQUIMICA Año: 2007 Tipo del documento: Article País de afiliación: Estados Unidos

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