Coherence analysis over the latent period of epileptogenesis reveal that high-frequency communication is increased across hemispheres in an animal model of limbic epilepsy.
Conf Proc IEEE Eng Med Biol Soc
; 2006: 1154-6, 2006.
Article
en En
| MEDLINE
| ID: mdl-17946026
ABSTRACT
A total of 32 microwire electrodes were implanted bilaterally into the hippocampus of Sprague-Dawley rats, which were then stimulated in the manner prescribed for the chronic limbic epilepsy model. After the initial seizure brought on by the stimulation, the animals were recorded at a high sampling rate (approximately 12 kHz) for the entire duration of the latent period. Coherence was calculated across channels in both stimulated (and later seizing) animals and non-stimulated (and thus non-seizing control) animals. Average coherence over time was greatest in intrahemispherical electrode pairs in both stimulated and non-stimulated animals. However, the 200-800 Hz band displays increased coherence interhemispherically and up to 200 Hz band displays decreased coherence interhemispherically this occurs only in stimulated animals.
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Banco de datos:
MEDLINE
Asunto principal:
Tiempo de Reacción
/
Algoritmos
/
Mapeo Encefálico
/
Epilepsia
/
Cerebro
/
Sistema Límbico
/
Modelos Neurológicos
Límite:
Animals
Idioma:
En
Revista:
Conf Proc IEEE Eng Med Biol Soc
Asunto de la revista:
ENGENHARIA BIOMEDICA
Año:
2006
Tipo del documento:
Article
País de afiliación:
Estados Unidos