Stenotrophomonas maltophilia responsible for respiratory infections in neonatal intensive care unit: antibiotic susceptibility and molecular typing.
Pathol Biol (Paris)
; 57(5): 363-7, 2009 Jul.
Article
en En
| MEDLINE
| ID: mdl-18178029
ABSTRACT
OBJECTIVE:
The aim of this study was to investigate the molecular epidemiology of Stenotrophomonas maltophilia strains responsible for respiratory infection in a neonatal intensive care unit (NICU) in Tunis City, isolated during 22 months (December 2003-September 2005). MATERIALS ANDMETHODS:
Twelve strains of S. maltophilia isolated from tracheal aspirates of distinct infants and two environmental strains were tested for antibiotic susceptibility and genotyped by pulsed-field gel electrophoresis (PFGE) method.RESULTS:
Unlike a large heterogeneity demonstrated by the antibiotyping method, PFGE identified two concomitant outbreaks consisting of nine, including an environmental strain (clone A), and four strains (clone B), respectively; a distinguishable strain was classified in a unique pattern (PFGE type C). The long-term dissemination of these strains is a characteristic feature of these outbreaks. Improvement of hygienic conditions attributed to a markedly decrease in their isolation frequencies. Concomitant outbreaks and long period persistence of S. maltophilia in NICU is an important finding of this study.CONCLUSION:
Identification of two clonal strains of S. maltophilia responsible of respiratory infection. Epidemic strains are hardly eradicated when colonization is established.
Texto completo:
1
Banco de datos:
MEDLINE
Asunto principal:
Traqueítis
/
Unidades de Cuidado Intensivo Neonatal
/
Infección Hospitalaria
/
Brotes de Enfermedades
/
Infecciones por Bacterias Gramnegativas
/
Stenotrophomonas maltophilia
Tipo de estudio:
Prognostic_studies
Límite:
Humans
/
Newborn
País/Región como asunto:
Africa
Idioma:
En
Revista:
Pathol Biol (Paris)
Año:
2009
Tipo del documento:
Article
País de afiliación:
Túnez