Severe acute mountain sickness and suspect high altitude cerebral edema related to nitroglycerin use.
High Alt Med Biol
; 9(3): 241-3, 2008.
Article
en En
| MEDLINE
| ID: mdl-18800963
ABSTRACT
An elite mountaineer reported severe acute mountain sickness and ataxia during an 8000-m expedition and concomitant use of transdermal nitroglycerin patches aimed to prevent frostbites. Use of nitroglycerin for this purpose is off-label, and its safety has not been assessed. Moreover, a relation between nitrate-induced cerebral vasodilation and high altitude cerebral edema is theoretically possible on a pathophysiological basis. It is our opinion that nitroglycerin use at high altitude should be discouraged, as efficacy in the prevention of frostbites is questionable and safety has not been assessed.
Texto completo:
1
Banco de datos:
MEDLINE
Asunto principal:
Vasodilatadores
/
Edema Encefálico
/
Nitroglicerina
/
Mal de Altura
Tipo de estudio:
Etiology_studies
/
Risk_factors_studies
Límite:
Humans
/
Male
/
Middle aged
Idioma:
En
Revista:
High Alt Med Biol
Asunto de la revista:
BIOLOGIA
/
MEDICINA
Año:
2008
Tipo del documento:
Article
País de afiliación:
Italia