Single proteins might have dual but related functions in intracellular and extracellular microenvironments.
Nat Rev Mol Cell Biol
; 10(3): 228-34, 2009 Mar.
Article
en En
| MEDLINE
| ID: mdl-19190671
ABSTRACT
The maintenance of organ homeostasis and the control of an appropriate response to environmental alterations require the intimate coordination of cellular functions and tissue organization. An important component of this coordination could be provided by proteins that can have distinct but linked functions on both sides of the plasma membrane. We present a model that proposes that unconventional secretion provides a mechanism through which single proteins can integrate complex tissue functions.
Texto completo:
1
Banco de datos:
MEDLINE
Asunto principal:
Proteínas
/
Citoplasma
/
Espacio Extracelular
Límite:
Animals
/
Humans
Idioma:
En
Revista:
Nat Rev Mol Cell Biol
Asunto de la revista:
BIOLOGIA MOLECULAR
Año:
2009
Tipo del documento:
Article
País de afiliación:
Estados Unidos