Essential fatty acid sufficiency does not preclude fat-soluble-vitamin deficiency in short-bowel syndrome.
Am J Clin Nutr
; 53(2): 499-502, 1991 Feb.
Article
en En
| MEDLINE
| ID: mdl-1989417
ABSTRACT
Patients with extensive small-bowel resection may experience malabsorption and nutrient deficiencies. We evaluated the ability to absorb fat and fat-soluble vitamins in a short-gut patient. For 18 wk after stopping intravenous lipid, while consuming a low-lactose, low-fat diet, he exhibited no clinical manifestations of essential fatty acid deficiency (EFAD). Serum 204n-6 (204 omega-6) and 182n-6 fatty acid concentrations were normal, whereas the concentration of 203n-9 remained less than or equal to 0.1% of total serum fatty acids. Although serum vitamin A was normal, beta-carotene was undetectable despite oral supplementation. Prothrombin time was elevated until parenteral vitamin K was given. This patient has fat absorption adequate to prevent EFAD but inadequate absorption of fat-soluble vitamins. In patients with short bowel, the requirements for parenteral lipids and fat-soluble vitamins should be determined independently.
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Banco de datos:
MEDLINE
Asunto principal:
Síndrome del Intestino Corto
/
Avitaminosis
/
Ácidos Grasos Esenciales
Tipo de estudio:
Etiology_studies
Límite:
Adult
/
Humans
/
Male
Idioma:
En
Revista:
Am J Clin Nutr
Año:
1991
Tipo del documento:
Article