A functional role for the ventrolateral prefrontal cortex in non-spatial auditory cognition.
Proc Natl Acad Sci U S A
; 106(47): 20045-50, 2009 Nov 24.
Article
en En
| MEDLINE
| ID: mdl-19897723
ABSTRACT
Spatial and non-spatial sensory information is hypothesized to be evaluated in parallel pathways. In this study, we tested the spatial and non-spatial sensitivity of auditory neurons in the ventrolateral prefrontal cortex (vPFC), a cortical area in the non-spatial pathway. Activity was tested while non-human primates reported changes in an auditory stimulus' spatial or non-spatial features. We found that vPFC neurons were reliably modulated during a non-spatial auditory task but were not modulated during a spatial auditory task. The degree of modulation during the non-spatial task correlated positively with the monkeys' behavioral performance. These results are consistent with the hypotheses that the vPFC is part of a circuit involved in non-spatial auditory processing and that the vPFC plays a functional role in non-spatial auditory cognition.
Texto completo:
1
Banco de datos:
MEDLINE
Asunto principal:
Percepción Auditiva
/
Corteza Prefrontal
/
Cognición
Límite:
Animals
/
Humans
/
Male
Idioma:
En
Revista:
Proc Natl Acad Sci U S A
Año:
2009
Tipo del documento:
Article
País de afiliación:
Estados Unidos