Radiofrequency ablation of liver metastases from cancer of unknown primary site.
Diagn Interv Radiol
; 15(4): 297-302, 2009 Dec.
Article
en En
| MEDLINE
| ID: mdl-19908183
ABSTRACT
PURPOSE:
This retrospective study was performed to review the efficacy of local radiofrequency ablation (RFA) in all the management of liver cancer of unknown primary site (CUP), and to identify possible prognostic features and complications that affect the efficacy of this treatment on survival. MATERIALS ANDMETHODS:
From April 2003 to December 2007, 22 patients (15 men, 7 women) with a total of 36 liver metastasis of CUP and poor response to prior systemic chemotherapy were treated with computed tomography-guided RFA. The median age of patients was 66 years. All patients (22/22) had 1-, 3-, and 6- month follow-up and 8/22 of them had a 12-month followup.RESULTS:
The overall median survival of all 22 patients was 10.9 months. Survival was better in patients with lesions 3 cm or smaller. No severe complications, including local seeding, were occured.CONCLUSION:
Our study revealed that RFA appears to be an effective, safe and relatively simple alternative procedure for the local ablation of these lesions. These results are more encouraging for lesions 3 cm or smaller, all of which were successfully treated, as proved by the imaging criteria and the statistical analysis. Further prospective trials are needed to determine whether RFA should be proposed for standard protocols.
Texto completo:
1
Banco de datos:
MEDLINE
Asunto principal:
Neoplasias Primarias Desconocidas
/
Terapia por Radiofrecuencia
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Neoplasias Hepáticas
Tipo de estudio:
Guideline
/
Observational_studies
/
Prognostic_studies
Límite:
Aged
/
Aged80
/
Female
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Humans
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Male
/
Middle aged
Idioma:
En
Revista:
Diagn Interv Radiol
Asunto de la revista:
DIAGNOSTICO POR IMAGEM
/
RADIOLOGIA
Año:
2009
Tipo del documento:
Article
País de afiliación:
Grecia