Coincidence of immune thrombocytopenia, intracranial hemorrhage and graft-versus-host disease in an 11-year-old girl.
Klin Padiatr
; 222(6): 378-82, 2010 Nov.
Article
en En
| MEDLINE
| ID: mdl-20830662
ABSTRACT
Primary immune thrombocytopenia (ITP) in children is usually self-limiting and harmless but can, rarely, result in life-threatening complications. The case of an 11-year-old girl with ITP is presented who developed recurrent intracranial hemorrhages followed by cerebral infarctions. The clinical course was complicated by a graft-versus-host disease involving several organs. Treatment was performed according to the current international consensus report of 2010 with glucocorticoids, immunoglobulin G, anti-D-immunoglobulin and additionally embolisation of the splenic artery. The girl survived. Reliable predictors, preventive measures for life-threatening complications in ITP and more information about the effectiveness and side-effects of the recommended treatment are urgently needed.
Texto completo:
1
Banco de datos:
MEDLINE
Asunto principal:
Púrpura Trombocitopénica Idiopática
/
Hemorragias Intracraneales
/
Enfermedad Injerto contra Huésped
Tipo de estudio:
Prognostic_studies
Límite:
Child
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Female
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Humans
Idioma:
En
Revista:
Klin Padiatr
Año:
2010
Tipo del documento:
Article
País de afiliación:
Alemania