Cryptotomography: reconstructing 3D Fourier intensities from randomly oriented single-shot diffraction patterns.
Phys Rev Lett
; 104(22): 225501, 2010 Jun 04.
Article
en En
| MEDLINE
| ID: mdl-20867179
ABSTRACT
We reconstructed the 3D Fourier intensity distribution of monodisperse prolate nanoparticles using single-shot 2D coherent diffraction patterns collected at DESY's FLASH facility when a bright, coherent, ultrafast x-ray pulse intercepted individual particles of random, unmeasured orientations. This first experimental demonstration of cryptotomography extended the expansion-maximization-compression framework to accommodate unmeasured fluctuations in photon fluence and loss of data due to saturation or background scatter. This work is an important step towards realizing single-shot diffraction imaging of single biomolecules.
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Banco de datos:
MEDLINE
Asunto principal:
Dispersión de Radiación
/
Tomografía
/
Imagenología Tridimensional
/
Análisis de Fourier
Tipo de estudio:
Clinical_trials
Idioma:
En
Revista:
Phys Rev Lett
Año:
2010
Tipo del documento:
Article
País de afiliación:
Estados Unidos