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Satellite DNAs contain sequences that induced curvature.
Martínez-Balbás, A; Rodríguez-Campos, A; García-Ramírez, M; Sainz, J; Carrera, P; Aymamí, J; Azorín, F.
Afiliación
  • Martínez-Balbás A; Grupo de Química Macromolecular, Centro de Investigación y Desarrollo del CSIC, ETSEIB, Barcelona, Spain.
Biochemistry ; 29(9): 2342-8, 1990 Mar 06.
Article en En | MEDLINE | ID: mdl-2110830
The repeating units of mouse, rat, and alpha-monkey satellites have been cloned. All three show properties that are characteristic of curved DNA: (i) their migration in polyacrylamide gels is slower than predicted from their sequences, and (ii) they appear as curved molecules when visualized by electron microscopy. All three satellite repeats contain runs of d(A.T)n greater than or equal to 3 residues that are likely to be responsible for their curvature. From analysis of 20 different satellite DNA sequences, we conclude that, in satellite DNA, adenine residues show a high tendency to cluster in groups of three or more.
Asunto(s)
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Banco de datos: MEDLINE Asunto principal: ADN Satélite Tipo de estudio: Prognostic_studies Límite: Animals Idioma: En Revista: Biochemistry Año: 1990 Tipo del documento: Article País de afiliación: España
Buscar en Google
Banco de datos: MEDLINE Asunto principal: ADN Satélite Tipo de estudio: Prognostic_studies Límite: Animals Idioma: En Revista: Biochemistry Año: 1990 Tipo del documento: Article País de afiliación: España