Fluoroquinolone-resistant Streptococcus agalactiae isolates from Argentina.
Rev Argent Microbiol
; 42(3): 203-7, 2010.
Article
en En
| MEDLINE
| ID: mdl-21180391
ABSTRACT
Fluoroquinolone resistance is a growing problem that has only recently emerged in S. agalactiae. Between 2005-2007, WHONET--Argentina network evaluated levofloxacin susceptibility in 1128 clinical S. agalactiae isolates, 10 (0.9%) of which proved to be resistant. Nine of them had come from 5 hospitals (in Buenos Aires City and 4 Argentinean provinces) and recovered from urine (n=7) and vaginal screening cultures (n=2). Three strains were also resistant to macrolides, lincosamides and B streptogramins due to the ermA gene. All nine fluoroquinolone-resistant isolates bore the same two mutations, Ser79Phe in ParC and Ser81Leu in GyrA proteins. Genetic relationships were analyzed by Apal-PFGE and two clones were determined, A (n=6) and B (n=3). To our knowledge, these are the first fluoroquinolone-resistant S. agalactiae isolates detected in Latin America.
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Banco de datos:
MEDLINE
Asunto principal:
Streptococcus agalactiae
/
Fluoroquinolonas
/
Antibacterianos
Tipo de estudio:
Clinical_trials
Límite:
Humans
País/Región como asunto:
America do sul
/
Argentina
Idioma:
En
Revista:
Rev Argent Microbiol
Año:
2010
Tipo del documento:
Article
País de afiliación:
Argentina