Isolation and characterisation of KP34--a novel φKMV-like bacteriophage for Klebsiella pneumoniae.
Appl Microbiol Biotechnol
; 90(4): 1333-45, 2011 May.
Article
en En
| MEDLINE
| ID: mdl-21327407
ABSTRACT
Bacteriophage KP34 is a novel virus belonging to the subfamily Autographivirinae lytic for extended-spectrum ß-lactamase-producing Klebsiella pneumoniae strains. Its biological features, morphology, susceptibility to chemical and physical agents, burst size, host specificity and activity spectrum were determined. As a potential antibacterial agent used in therapy, KP34 molecular features including genome sequence and protein composition were examined. Phylogenetic analyses and clustering of KP34 phage genome sequences revealed its clear relationships with "phiKMV-like viruses". Simultaneously, whole-genome analyses permitted clustering and classification of all phages, with completely sequenced genomes, belonging to the Podoviridae.
Texto completo:
1
Banco de datos:
MEDLINE
Asunto principal:
Aguas del Alcantarillado
/
Bacteriófagos
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Podoviridae
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Klebsiella pneumoniae
Idioma:
En
Revista:
Appl Microbiol Biotechnol
Año:
2011
Tipo del documento:
Article
País de afiliación:
Polonia