Iron insufficiency and hypovitaminosis D in adolescents with chronic fatigue and orthostatic intolerance.
South Med J
; 104(8): 609-11, 2011 Aug.
Article
en En
| MEDLINE
| ID: mdl-21886073
ABSTRACT
OBJECTIVES:
More than 10% of adolescents suffer from severe fatigue and/or orthostatic intolerance. Adult studies show correlations between iron insufficiency and fatigue as well as between hypovitaminosis D and non-specific pain. We sought to determine whether there were correlations between nutritional factors (iron status, and serum vitamin D levels) and chronic ill health.METHODS:
We reviewed records of 188 adolescents with symptoms of fatigue and/or orthostatic intolerance and who underwent autonomic reflex screening.RESULTS:
Of the 188 patients, 130 patients (69%) had excessive postural tachycardia (PT) with a heart rate (HR) change of ≥30 bpm. 62 patients (47%, n = 131) had iron insufficiency with low iron stores, and 29 patients (22%, n = 131) were iron deficient. HR change did not correlate to ferritin level (P = 0.15). 21 patients (22%, n = 95) had hypovitaminosis D (25-hydroxyvitamin D ≤20 ng/mL). There was a significant association with hypovitaminosis D and orthostatic intolerance (P = 0.024).CONCLUSION:
In patients presenting with chronic fatigue and/or orthostatic intolerance, low ferritin levels and hypovitaminosis D are common, especially in patients with PT.
Texto completo:
1
Banco de datos:
MEDLINE
Asunto principal:
Deficiencia de Vitamina D
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Síndrome de Fatiga Crónica
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Síndrome de Taquicardia Postural Ortostática
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Hierro
Tipo de estudio:
Observational_studies
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Risk_factors_studies
Límite:
Adolescent
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Female
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Humans
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Male
Idioma:
En
Revista:
South Med J
Año:
2011
Tipo del documento:
Article
País de afiliación:
Estados Unidos