Eight years of Legionnaires' disease transmission in travellers to a condominium complex in Las Vegas, Nevada.
Epidemiol Infect
; 140(11): 1993-2002, 2012 Nov.
Article
en En
| MEDLINE
| ID: mdl-22214820
ABSTRACT
Travel is a risk factor for Legionnaires' disease. In 2008, two cases were reported in condominium guests where we investigated a 2001 outbreak. We reinvestigated to identify additional cases and determine whether ongoing transmission resulted from persistent colonization of potable water. Exposures were assessed by matched case-control analyses (2001) and case-series interviews (2008). We sampled potable water and other water sources. Isolates were compared using sequence-based typing. From 2001 to 2008, 35 cases were identified. Confirmed cases reported after the cluster in 2001-2002 were initially considered sporadic, but retrospective case-finding identified five additional cases. Cases were more likely than controls to stay in tower 2 of the condominium [matched odds ratio (mOR) 6·1, 95% confidence interval (CI) 1·6-22·9]; transmission was associated with showering duration (mOR 23·0, 95% CI 1·4-384). We characterized a clinical isolate as sequence type 35 (ST35) and detected ST35 in samples of tower 2's potable water in 2001, 2002, and 2008. This prolonged outbreak illustrates the importance of striving for permanent Legionella eradication from potable water.
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Banco de datos:
MEDLINE
Asunto principal:
Viaje
/
Microbiología del Agua
/
Agua Potable
/
Enfermedad de los Legionarios
/
Brotes de Enfermedades
/
Trazado de Contacto
/
Legionella pneumophila
Tipo de estudio:
Diagnostic_studies
/
Etiology_studies
/
Observational_studies
/
Prognostic_studies
/
Risk_factors_studies
Límite:
Aged
/
Humans
/
Middle aged
País/Región como asunto:
America do norte
Idioma:
En
Revista:
Epidemiol Infect
Asunto de la revista:
DOENCAS TRANSMISSIVEIS
/
EPIDEMIOLOGIA
Año:
2012
Tipo del documento:
Article
País de afiliación:
Estados Unidos