[The genetic safety of induced pluripotent stem (iPS) cells].
Yi Chuan
; 34(3): 260-8, 2012 Mar.
Article
en Zh
| MEDLINE
| ID: mdl-22425944
ABSTRACT
Since Takahashi and Yamanaka first generated induced pluripotent stem (iPS) cells from mouse fibroblasts successfully in 2006, iPS cells have rapidly become a new hotspot in the field of stem cells research because of their broad potential application prospects. Meanwhile, more and more attentions are paid to the genetic safety of iPS cells. This article summarizes recent findings on genetic safety of iPS cells and reviews the possible causes leading to genetic instability of iPS cells. Hopefully, this review is helpful to improve the induction of iPS cells and obtain genetically safe iPS cells.
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Banco de datos:
MEDLINE
Asunto principal:
Seguridad
/
Técnicas Genéticas
/
Células Madre Pluripotentes Inducidas
Límite:
Animals
/
Humans
Idioma:
Zh
Revista:
Yi Chuan
Asunto de la revista:
GENETICA
Año:
2012
Tipo del documento:
Article
País de afiliación:
China