[Triglyceride (TG) and remnant lipoproteins].
Rinsho Byori
; 60(4): 343-8, 2012 Apr.
Article
en Ja
| MEDLINE
| ID: mdl-22686044
ABSTRACT
Lowering low-density lipoprotein (LDL) cholesterol (LDL-C) can reduce the risk of cardiovascular disease (CVD) by approximately 30%, and the remaining 70% should be the second front of CVD risk reduction. Such residual risks include high triglyceride (TG) concentrations and low levels of high-density lipoprotein (HDL) cholesterol (HDL-C) in terms of dyslipidemia. TG-rich lipoproteins are heterogenous and composed of a variety of subfractions, all of which are not necessarily relevant to atherosclerosis and CVD risk. However, remnant lipoproteins, TG-rich lipoproteins, are atherogenic and related to CVD risk. Two different methods (RLP-C and RemL-C) have been developed to measure cholesterol levels of remnant lipoproteins. Although there is a difference in affinity to intermediate-density lipoprotein (IDL) between the two methods, they may be better qualified as biomarkers of CVD risk than TG itself. TG measurements play a certain role in the evaluation of CVD risk, but the remnant lipoprotein cholesterol measurement can provide better screening for patients at high CVD risk than TG and may be a useful examination in both quantity and quality.
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Banco de datos:
MEDLINE
Asunto principal:
Triglicéridos
/
Enfermedades Cardiovasculares
/
Lipoproteínas
Límite:
Humans
Idioma:
Ja
Revista:
Rinsho Byori
Año:
2012
Tipo del documento:
Article
País de afiliación:
Japón