[CSF RT-PCR standardization in pediatric patients with enteroviral central nervous system infection]. / Estandarización de RT-PCR en LCR de pacientes pediátricos con infección del sistema nervioso central por enterovirus.
Rev Invest Clin
; 64(1): 59-66, 2012.
Article
en Es
| MEDLINE
| ID: mdl-22690530
ABSTRACT
OBJECTIVE:
We standardized the RT-PCR panviral CSF and determined its applicability in detecting acute enterovirus infection in the central nervous system in children under 15 years. MATERIAL ANDMETHODS:
RT-PCR was performed directly in CSF samples of 10 pediatric patients with suspected CNS infection and 9, with different conditions of the central nervous system.RESULTS:
80% (8/10) of RT-PCR samples were positive for enterovirus in patients with suspected CNS infection and no sample was positive in patients with different ailments.CONCLUSIONS:
Since enteroviruses are among the main etiologies of pediatric encephalitis, RT-PCR could be particularly useful for rapid detection in CSF.
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Banco de datos:
MEDLINE
Asunto principal:
Encefalitis Viral
/
Reacción en Cadena de la Polimerasa de Transcriptasa Inversa
/
Infecciones por Enterovirus
/
Meningitis Aséptica
Tipo de estudio:
Diagnostic_studies
/
Etiology_studies
Límite:
Child
/
Child, preschool
/
Female
/
Humans
/
Infant
/
Male
Idioma:
Es
Revista:
Rev Invest Clin
Asunto de la revista:
MEDICINA
Año:
2012
Tipo del documento:
Article