Gene-environment studies and borderline personality disorder: a review.
Curr Psychiatry Rep
; 15(1): 336, 2013 Jan.
Article
en En
| MEDLINE
| ID: mdl-23250817
ABSTRACT
We review recent gene-environment studies relevant to borderline personality disorder, including those focusing on impulsivity, emotion sensitivity, suicidal behavior, aggression and anger, and the borderline personality phenotype itself. Almost all the studies reviewed suffered from a number of methodological and statistical problems, limiting the conclusions that currently can be drawn. The best evidence to date supports a gene-environment correlation (rGE) model for borderline personality traits and a range of adverse life events, indicating that those at risk for BPD are also at increased risk for exposure to environments that may trigger BPD. We provide suggestions regarding future research on GxE interaction and rGE effects in borderline personality.
Texto completo:
1
Banco de datos:
MEDLINE
Asunto principal:
Trastorno de Personalidad Limítrofe
/
Interacción Gen-Ambiente
Tipo de estudio:
Etiology_studies
/
Prognostic_studies
/
Risk_factors_studies
Límite:
Humans
Idioma:
En
Revista:
Curr Psychiatry Rep
Asunto de la revista:
PSIQUIATRIA
Año:
2013
Tipo del documento:
Article
País de afiliación:
Estados Unidos